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Foreign Pharmacy Graduate Equivalency Examination Question and Answers

Foreign Pharmacy Graduate Equivalency Examination

Last Update May 18, 2024
Total Questions : 426

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Questions 1

Potassium sparing diuretics have the primary effect upon the _____ found in the kidney.

Options:

A.  

Proximal convoluted tubule

B.  

Loop of Henle

C.  

Collecting duct

D.  

Distal convoluted tubule

Discussion 0
Questions 2

Sulfinpyrazone is used as a(n):

Options:

A.  

analgesic agent

B.  

antipyretic agent

C.  

anti-inflammatory agent

D.  

agent which increases renal tubular reabsorption of uric acid

E.  

uricosuric agent

Discussion 0
Questions 3

The mechanism of antipsychotic effect of phenothiazines is thought to be due to:

Options:

A.  

improvement of cholinergic transmission

B.  

blockade of catecholamine re-uptake

C.  

blockade of dopamine receptors

D.  

blockade of enkephalinergic neurons

E.  

prolactin release

Discussion 0
Questions 4

Organisms commonly implicated in the cause of Traveller's Diarrhea include:

I Bacteroides fragilis

II Escherichia coli

III Shigella sp

Options:

A.  

I only

B.  

III only

C.  

I and II only

D.  

II and III only

E.  

I, II and III

Discussion 0
Questions 5

Drug of choice in the treatment of chronic obstructive pulmonary disease may include:

Options:

A.  

Salbutamol

B.  

Ipratropium

C.  

Salmereol

D.  

Sodium cromoglycate

E.  

Fluticasone

Discussion 0
Questions 6

The style of management in which the owner of a pharmacy emphasizes the development of detailed policies and written procedures for employees to observe at all times is referred to as:

Options:

A.  

autocratic

B.  

bureaucratic

C.  

participative

D.  

benevolent

E.  

consultative

Discussion 0
Questions 7

The method of ionization of mass spectrometry which results in well-established diagnostic fragmentation patterns that are useful in the identification of compounds of unknown structure is called:

Options:

A.  

atmospheric pressure chemical ionization (APCI)

B.  

chemical ionization (CI)

C.  

electron impact (EI) ionization

D.  

electrospray ionization (ESI)

E.  

fast atom bombardment (FAB. ionization

F.  

Pharmacy Practice

Discussion 0
Questions 8

Pannus is an inflammatory exudates characterized by:

I- Synovial cell proliferation inside of a joint

II- Normally occurs in patients with rheumatoid arthritis

III- An immunologic complication

Options:

A.  

I only

B.  

III only

C.  

I and II only

D.  

II and III only

E.  

All are correct

Discussion 0
Questions 9

An angiotensin-converting enzyme (ACE. inhibitor for which both renal elimination and metabolism are important in the elimination of the drug and its active metabolites is:

Options:

A.  

enalapril

B.  

fosinopril

C.  

lisinopril

D.  

quinapril

E.  

ramipril

Discussion 0
Questions 10

Diflunisal is most likely to be prescribed for the treatment of:

Options:

A.  

Wilson’s disease

B.  

Rheumatoid arthritis

C.  

Cysteinuria

D.  

Psoriasis

E.  

Hansen’s disease

Discussion 0
Questions 11

Dopamine is useful in the treatment of cardiogenic shock because it:

I selectively dilates renal and mesenteric vascular beds.

II does not induce peripheral vasoconstriction.

III decreases the force of myocardial contraction.

Options:

A.  

I only

B.  

III only

C.  

I and II only

D.  

II and III only

E.  

I, II and III

Discussion 0
Questions 12

Five subjects given a single intravenous dose of a drug have the following elimination half-lives: 3, 9, 6, 5 and 4 h (hours). The mean half-life is:

Options:

A.  

4.0 h.

B.  

5.0 h.

C.  

5.4 h.

D.  

5.8 h.

E.  

6.0 h.

Discussion 0
Questions 13

The Latin abbreviation for "before meals" is:

Options:

A.  

ac

B.  

aa

C.  

pc

D.  

ic

E.  

cc

Discussion 0
Questions 14

An oral chelating agent used in the treatment of rheumatoid arthritis is:

Options:

A.  

Allopurinol

B.  

Sulphinpyrazone

C.  

Indomethacin

D.  

Penicillamine

E.  

Methotrexate

Discussion 0
Questions 15

Which financial statement could be used to determine the total value of prescription drug sales for a pharmacy during the course of a year?

Options:

A.  

Balance sheet

B.  

Statement of investments

C.  

Statement of changes in financial position

D.  

Income statement

E.  

Statement of equity

Discussion 0
Questions 16

Drug considered as the drug of choice in a specific asthma emergency treatment include:

Options:

A.  

Salmeterol

B.  

Adrenaline

C.  

Albuterol

D.  

Cortisone

E.  

Zafirlukst

Discussion 0
Questions 17

Intra-articular means:

Options:

A.  

In the joint space

B.  

In the tissues space

C.  

In the spinal fluid

D.  

In the spinal column

E.  

In the dermis

Discussion 0
Questions 18

Which of the following hormone acts on cell wall?

Options:

A.  

Insulin

B.  

Prolactin

C.  

Cortisol

D.  

Estrogen

E.  

Alanine

Discussion 0
Questions 19

Which vitamin can be classified as hormone?

Options:

A.  

Vitamin D

B.  

Vitamin D3

C.  

Vitamin E

D.  

Vitamin K

E.  

Vitamin B12

Discussion 0
Questions 20

In an enzymatic reaction, addition of competitive inhibitor leads to:

Options:

A.  

Increase the rate of reaction

B.  

Decrease the rate of reaction

C.  

Same rate of reaction

D.  

Decrease rate and increase substrate concentration

E.  

Decrease both rate and substrate concentration

Discussion 0
Questions 21

Which of the following is the only disaccharide NOT synthesized during human metabolism?

Options:

A.  

Lactose

B.  

Maltase

C.  

Fructose

D.  

Glucose

E.  

Cellulose

Discussion 0
Questions 22

Which of the following is considered a class IA Sodium Channel blocker?

Options:

A.  

Propafenone

B.  

Disopyramide

C.  

Aminodarone

D.  

Quinidine

Discussion 0
Questions 23

dication of ciprofloxacin is:

Options:

A.  

In Tuberculosis

B.  

Migraine prophylaxis

C.  

Tricyclic antidepressant poisoning

D.  

Broad spectrum antibacterial agent

E.  

Asthma

Discussion 0
Questions 24

Mechanism of action of cefoxitin is:

Options:

A.  

monoamine reuptake inhibitor

B.  

Inhibits cholesterol synthesis

C.  

Inhibits activation of GPIIb/IIIa

D.  

Inhibits transpeptidase

E.  

Inhibits Na-K-2Cl transporter

Discussion 0
Questions 25

Which of the following is considered a class IA Sodium Channel blocker?

Options:

A.  

Mexiletine

B.  

Aminodarone

C.  

Quinidine

D.  

Procainamide

Discussion 0
Questions 26

Indication of PTU is:

Options:

A.  

Glaucoma

B.  

Migraine prophylaxis

C.  

Thyrotoxicosis - preparation for radioactive iodine therapy

D.  

Severe recurrent ventricular tachyarrhythmias

E.  

Broad spectrum antibacterial agent

Discussion 0
Questions 27

Indication of salmeterol is:

Options:

A.  

Thyrotoxicosis - preparation for surgery

B.  

Chronic renal disease

C.  

Scleroderma renal crisis

D.  

Asthma

E.  

Allergic rhinitis

Discussion 0
Questions 28

Side effect of fluvastatin is:

Options:

A.  

Seizures

B.  

Skin rash

C.  

Nausea

D.  

Urinary tract complications

E.  

Myalgia

Discussion 0
Questions 29

Cigarette smoke causes an increase in levels of CYP1A isozymes. Theophylline is primarily metabolized by the CYP1A system. What would happen to theophylline clearance for an asthmatic patient in hospital who could not smoke?

Options:

A.  

No change

B.  

Increase

C.  

Decrease

Discussion 0
Questions 30

Which of the following statements refers to phenelzine?

Options:

A.  

Mechanism of action probably involves NO.

B.  

Rapid IV infusion predisposes to neuromuscular paralysis.

C.  

May work when other antidepressants fail.

D.  

Long half-life.

E.  

MOA is inhibited irreversibly. Response occurs when >80% platelet MOA is inhibited.

Discussion 0
Questions 31

Route of administration of interferon alpha is:

Options:

A.  

Intramuscular

B.  

Inhalation

C.  

Topical

D.  

Oral

E.  

Intra-auricular

Discussion 0
Questions 32

Which of the following is the main carbohydrate of body blood?

Options:

A.  

Sorbitol

B.  

Mannitol

C.  

Frutase

D.  

Glucase

E.  

Lactase

Discussion 0
Questions 33

Which of the following is the predominant intracellular element?

Options:

A.  

Sodium

B.  

Magnesium

C.  

Potassium

D.  

Calcium

E.  

Phosphorous

Discussion 0
Questions 34

Which of the following reactions is controlled by the pancreatic hormone INSULIN?

Options:

A.  

Glycogenolysis

B.  

Glycolysis

C.  

Glycogenesis

D.  

Gluconeogenesis

E.  

Anaerobic glycolysis

Discussion 0
Questions 35

Tetrodotoxin is a selective inhibitor of the:

Options:

A.  

calcium ion channel

B.  

sodium ion channel

C.  

potassium ion channel

D.  

chloride ion channel

E.  

nicotinic ion channel

Discussion 0
Questions 36

Correct statements regarding RNA messenger may include:

Options:

A.  

Carrier activated aminoacids to the ribosome

B.  

Specifies aminoacids sequence templant for protein synthesis

C.  

Enable DNA fragments to be joined

D.  

Synthesize RNA

E.  

Carrier the genetic information for all the other cells

Discussion 0
Questions 37

The codon sequence Adenine-Guanine-Cytosine-Uracil is seen in

I- RNAs

II- DNAs

III- Both DNAs and RNAs

Options:

A.  

I only

B.  

III only

C.  

I and II only

D.  

II and III only

E.  

All are correct

Discussion 0
Questions 38

Carotene is the precursor of:

Options:

A.  

retinol

B.  

thiamine

C.  

calciferol

D.  

riboflavin

E.  

retinoic acid

Discussion 0
Questions 39

The conversion of β-carotene to vitamin A is carried out in:

Options:

A.  

Pancreas

B.  

Spleen

C.  

Liver

D.  

Adrenal cortex

E.  

Nefrons

Discussion 0
Questions 40

Which of the following statements is/are correct regarding enzymes?

I-Enzymes are proteins

II- Enzymes are catalyst because they are never altered during a reaction

III- Michaelis-Menten theory describe the enzymatic reactions

Options:

A.  

I only

B.  

III only

C.  

I and II only

D.  

II and III only

E.  

All are correct

Discussion 0
Questions 41

Example of compound that is phospholipids include:

Options:

A.  

Glycogen

B.  

Leucine

C.  

Lecithin

D.  

Hyaluronic acid

E.  

Phenylalanine

Discussion 0
Questions 42

Indication of ticarcillin is:

Options:

A.  

Streptococcus pneumoniae

B.  

Varicella zoster virus

C.  

Myocardial infarction

D.  

Generalized motor seizures

E.  

Bone marrow failure states (aplastic anemia, myelodysplasias) (investigational)

Discussion 0
Questions 43

For the majority of drugs, which of the following equations correctly defines clearance?

Options:

A.  

Cl = Elimination rate/Cp

B.  

Cl = QxE

C.  

Cl = .7VD/t1/2

D.  

All are correct

Discussion 0
Questions 44

Route of administration of ofloxacin is:

Options:

A.  

Intra-auricular

B.  

Sublingual

C.  

Oral

D.  

IV

E.  

Intramuscular

Discussion 0
Questions 45

Mechanism of action of vancomycin is:

Options:

A.  

Potentiates glucose-mediated insulin secretion

B.  

Inhibits phospholipase C

C.  

Mitotic spindle poison

D.  

Inhibits transpeptidase

E.  

Inhibits bacterial cell wall synthesis

Discussion 0
Questions 46

Which of the following statements refers to etidronate?

Options:

A.  

Binds to DNA, preferentially to GC pairs. Inhibits RNA, DNA, and protein synthesis.

B.  

Human, pig, salmon, and eel calcitonins are available.

C.  

Is used for both therapy and prophylaxis of influenza A.

D.  

Bioavailability increases with administered dose.

E.  

Only approved by FDA for hypertension treatment.

Discussion 0
Questions 47

Catabolism of carbohydrates is a process characterized by:

I- Consume of energy

II- Release stored energy from carbohydrates

III-Glycogenolysis is an example of carbohydrates catabolism reaction

Options:

A.  

I only

B.  

III only

C.  

I and II only

D.  

II and III only

E.  

All are correct

Discussion 0
Questions 48

Which of the following vitamin is the precursor of collagen synthesis?

Options:

A.  

Vitanin A

B.  

Vitamin B

C.  

Vitamin C

D.  

Vitamin D

E.  

Vitamin E

Discussion 0
Questions 49

All of the following are examples of amino penicillin, EXCEPT:

Options:

A.  

Ampicillin

B.  

Cloxacillin

C.  

Amoxicillin

D.  

Bicampicilin

E.  

All are correct

Discussion 0
Questions 50

Which of the following statement is RIGHT regarding influenza treatment?

I- Type A influenza is best treated by amantadine and rimantadine

II- Type B influenza is best treated by oseltamivir and zenamivir

III- Influenza should not be treated with antiviral agents

Options:

A.  

I only

B.  

III only

C.  

I and II only

D.  

II and III only

E.  

All are correct

Discussion 0
Questions 51

Which of the following statement is/are correct regarding Gray Babies syndrome?

I- Occurs in premature and new born infants when choramphenicol is administrated during the first few days of life

II- Due to inability of the infant to metabolize the drug because of glucoronyl transferase deficiency

III- Glucoronyl transferase is required to detoxify cloramphenicol

Options:

A.  

I only

B.  

III only

C.  

I and II only

D.  

II and III only

E.  

All are correct

Discussion 0
Questions 52

All of the following are narrow spectrum protein synthesis inhibitors, EXCEPT:

Options:

A.  

Erythromycin

B.  

Azithromycin

C.  

Clarithromycin

D.  

Tetracycline

E.  

Clindamycin

Discussion 0
Questions 53

Wrong statement regarding antifungal agents includes which of the following?

Options:

A.  

Polyene antifungal act binding to ergosterol from pores resulting in linkage of cellular.

B.  

Azoles antifungal act blocking the synthesis of ergosterol.

C.  

Polyene antifungal has the widest spectrum compared to any other agent

D.  

Side effects of antifungals include fever, chills, anorexia, headaches and muscle pain

E.  

Side effects of antifungals cannot be treat for Tylenol due to high drug interaction.

Discussion 0
Questions 54

Examples of antibiotic that is an acid stable penicillinase resistant include:

Options:

A.  

Amoxicillin

B.  

Oxacillin

C.  

Ampicillin

D.  

Carbenicillin

E.  

Penicillin V

Discussion 0
Questions 55

Class of cocaine is:

Options:

A.  

Retinoids

B.  

Anti-asthmatic agents

C.  

Autonomic nervous system drugs

D.  

Loop diuretics

E.  

Antiarrhythmic agents

Discussion 0
Questions 56

Correct statements regarding aminoglycosides may include:

I- Has a half-life of 12hours

II- The effect continue remain after all drug is eliminated

III- The relation plasma concentration and half-life is not clear

Options:

A.  

I only

B.  

III only

C.  

I and II only

D.  

II and III only

E.  

All are correct

Discussion 0
Questions 57

Which of the following agents may best treat Meningococcal encephalitis?

Options:

A.  

Sulfametoxazole

B.  

Erythromycin

C.  

Cephalexin

D.  

Tetracycline

E.  

Penicillin

Discussion 0
Questions 58

All of the following are examples of quinolone antimicrobial agents, EXCEPT

Options:

A.  

Cephalexin

B.  

Ofloxacin

C.  

Norfloxacin

D.  

Ciprofloxacin

E.  

Levofloxacin

Discussion 0
Questions 59

The only antibiotic available as chew able tablet includes:

Options:

A.  

Penicillin

B.  

Amoxicillin

C.  

Ampicillin

D.  

Erythromycin

E.  

Clarithromycin

Discussion 0
Questions 60

Mechanism of action of salbutamol is:

Options:

A.  

opiate agonist

B.  

Blocks sustained repetitive neuronal firing

C.  

beta-2 agonist

D.  

Inhibits phospholipase A2

E.  

Inhibits phospholipase C

Discussion 0
Questions 61

Which of the following complications is considered the gravest side effect associated with isoniazid treatment?

Options:

A.  

Cardiac dysfunction

B.  

Mental dysfunction

C.  

Hepatitis

D.  

Renal complications

E.  

Discoloration of skin

Discussion 0
Questions 62

Class of timolol is:

Options:

A.  

Antiarrhythmic agents

B.  

Antithyroid agents

C.  

Anticonvulsants

D.  

Beta blockers

E.  

Antidepressants

Discussion 0
Questions 63

Colitis associated with antibiotic use can best be treated by:

Options:

A.  

Cephalosporins

B.  

Macrolides

C.  

Aminoglycosides

D.  

Vancomycin

E.  

Penicillin

Discussion 0
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